MindMap Gallery Malignancy causing flank pain

Malignancy causing flank pain

Malignancy is a term for diseases in which abnormal cells divide without control and can invade nearby tissues. Malignant cells can also spread to other parts of the body through the blood and lymph systems.

Edited at 2021-12-09 01:50:16

Aisha AA

Malignancy causing flank pain

Aisha AA

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Outline

MALIGNANCIES ASSOCIATED WITH FLANK PAIN

RENAL CELL CARCINOMA

Adenocarcinoma from tubular epithelial cells (PCT) (80-90% of malignant tumors of the kidney)

RISK FACTORS: men > women (60-70 yo) | smoking | obesity | ACKD in ESRD | von Hippel-Lindau dse

COMMON FORMS: ~CLEAR CELL CA (80%) ~PAPILLARY RENAL CA (15%) ~ CHROMOPHOBE RENAL CA (<5%)

DIAGNOSTICS: RENAL UTZ | CT | histology

TREATMENT: Surgical resection | radiation / chemo

TRANSITIONAL CELL CARCINOMA

MOST COMMON tumor of UTS (renal calyces, renal pelvis ureters, bladders) ~Arise in th UT outside of kidney, predominantly in the bladder, originating form transitional epithelium

affect men > women (50 - 70 years)

associated with problems in your Pee SAC: phenacetin | Smoking | Aniline Dyes | Cyclophosphamide

DIAGNOSIS: Cystoscopy | urine cytology | pelvic CT

TREATMENT: ~ Transurethral resection / injection of chemotherapeutic agents into the bladder. ~ Cystectomy ~ Radiation / Chemotherapy / both

VON HIPPEL-LINDAU DISEASE

An INHERITED CANCER SYNDROME with renal manifestations

caused by mutations in VHL tumor suppressor gene.

DIAGNOSTICS: annual screening of the kidneys ~ CT / MRI

MANAGEMENT : - Nephron-sapring surgical approaches for removal of cancerous lesions

PROSTATE CANCER

most common ca in men. 2nd leading cause of ca death in men

RISK FACTORS: advanced age | + family history

DIAGNOSTICS: markedly increased PSA ( >4 ng/mL) | utz0guided transrectal biopsy | Gleason histologic syst. | CT to look for metastases | bone scan

TREATMENT: observation | Radical prostatectomy | radiation therapy | PSA | androgen ablation

PANCREATIC CANCER

"SILENT DSE"

manifests as dull left flank pain

negative findings on an UTZ study (symptoms can be quite vague, and theycan vary depending on the location of cancer in the pancreas)

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