autonomic nervous system

A mind map about autonomic nervous system.

Edited at 2020-09-08 01:24:17

Roy Mustang

autonomic nervous system

Roy Mustang

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Outline

Autonomic Nervous System

Parasympathomimetics

Cholinergic Antagonists

Adrenergic Antagonists

Adrenergic Agonists

Allergies

Cardiac, vascular conditions

Bronchial asthma

Premature labour

Mydriatic, hypoglycemia

Choline Esters

Cholinomimetic Alkaloids

Cholinesterase Inhibitors

Prevents binding of ACh to AChE

Reduces rate of hydrolysis, increases cholinergic effects

Form intermediates with ACE, or act as pure competitive inhibitors

Pharmacological Effects

Digestive Tract

Increase GI motility, peristalsis

Increase frequency and strength of peristalisis: defecation

Ocular Effects

Pupillary constriction, spasm of accomodation

Skeletal Muscle

Anticurare agents

Depolarizing agents - stimulating effect

Ganglionic stimulation, hypotension, bradycardia, arrhythmia

Contraction of bladder, bronchoconstriction

Toxicology

Contraindicated for impaction with obstruction, pregnancy

Pupil constriction, dyspnea, bradycardia, hypotension

Respiratory paralysis + increased bronchiolar secretion (death)

Neostigmine: skeletal muscle weakness, nausea, vomiting, colic, diarrhea

Physostigmine: stimulation followed by CNS depression, convulsions

Treatment: Atropine

Cholinergic Antagonists

Antimuscarinic Agents

Ganglionic Blockers

Target Nn-receptors

Neuromuscular Blockers

Target Nm-receptors